Valdecoxib


w84



General information:


Withdrawn ID: w84
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): M01AH03
Molecular Formula: C16H14N2O3S
Molweight: 314.359



Withdrawal information:


Withdrawn due to drug safety reasons:Yes
First approved: 2001
First withdrawn: 2004
Last withdrawn: 2004
Reference: https://www.ncbi.nlm.nih.gov/pubmed/18193817



Side-effects:

Total reported cases (submitted by medical professionals) with Valdecoxib as primary suspect: 4138


Reported final outcomes:
Hospitalization (initial or prolonged): 1977
Death: 495
Disability: 182
Life-Threatening condition: 112
Intervention required to prevent permanent impairment/damage: 46
Congenital anomaly: 3


Reported side-effects:

Side-effect Case number
MYOCARDIAL INFARCTION1212
CEREBROVASCULAR ACCIDENT1149
STEVENS-JOHNSON SYNDROME804
CARDIOVASCULAR DISORDER328
DEPRESSION297
ANXIETY217
THROMBOSIS205
PULMONARY EMBOLISM172
RASH149
ARRHYTHMIA137
HYPERTENSION131
ORGAN FAILURE113
AMNESIA111
TRANSIENT ISCHAEMIC ATTACK99
CARDIAC FAILURE CONGESTIVE91
DYSPNOEA89
CHEST PAIN88
CARDIAC DISORDER81
DRUG INEFFECTIVE68
GASTROINTESTINAL HAEMORRHAGE66
ACUTE MYOCARDIAL INFARCTION66
CARDIAC ARREST64
PAIN63
NAUSEA59
HEADACHE57
RENAL FAILURE54
HYPERSENSITIVITY54
PRURITUS53
URTICARIA52
DRUG HYPERSENSITIVITY49
DIZZINESS49
DEEP VEIN THROMBOSIS49
CORONARY ARTERY DISEASE49
FATIGUE44
ERYTHEMA MULTIFORME44
OEDEMA PERIPHERAL41
SKIN REACTION40
WEIGHT DECREASED39
INJURY37
ASTHENIA37
VOMITING36
INSOMNIA36
FALL36
RENAL FAILURE ACUTE35
ARTHRALGIA35
FEELING ABNORMAL34
ERYTHEMA34
PYREXIA33
CONDITION AGGRAVATED33
BLOOD PRESSURE INCREASED33
BLINDNESS33
PAIN IN EXTREMITY32
DIARRHOEA32
CARDIAC FAILURE32
ATRIAL FIBRILLATION32
PALPITATIONS31
HAEMORRHAGE31
CORONARY ARTERY OCCLUSION30
ISCHAEMIC STROKE29
DYSPHAGIA29
MALAISE28
BLISTER28
BACK PAIN28
ABDOMINAL PAIN UPPER28
SCAR27
HEART RATE INCREASED27
DEATH27
RENAL DISORDER26
HYPOAESTHESIA26
ANGINA PECTORIS26
ABDOMINAL PAIN26
SKIN EXFOLIATION25
RASH GENERALISED25
RASH ERYTHEMATOUS25
MUSCLE SPASMS25
GASTROOESOPHAGEAL REFLUX DISEASE24
CONVULSION24
CEREBRAL INFARCTION24
BLOOD CHOLESTEROL INCREASED24
SKIN DISCOLOURATION23
RASH PRURITIC23
DRUG INTERACTION23
DERMATITIS23
WEIGHT INCREASED22
SWELLING FACE22
HYPOTENSION22
ARTHRITIS22
ANAEMIA22
TOXIC EPIDERMAL NECROLYSIS21
NERVOUSNESS21
DYSPEPSIA21
CEREBROVASCULAR DISORDER20
RASH MACULO-PAPULAR19
HEMIPARESIS19
DIABETES MELLITUS19
CONTUSION19
ARTERIOSCLEROSIS19
PARAESTHESIA18
LOSS OF CONSCIOUSNESS18
EXANTHEM18
PNEUMONIA17
CHILLS17
SKIN LESION16
CONFUSIONAL STATE16
VISUAL DISTURBANCE15
SYNCOPE15
SWELLING15
STOMACH DISCOMFORT15
RESPIRATORY FAILURE15
MYALGIA15
MELAENA15
ECZEMA15
DRUG ERUPTION15
DEHYDRATION15
BLINDNESS UNILATERAL15
ASTHMA15
ARTERIAL OCCLUSIVE DISEASE15
VISION BLURRED14
UNEVALUABLE EVENT14
SKIN DISORDER14
SEPSIS14
PANIC ATTACK14
IMPAIRED HEALING14
HYPERHIDROSIS14
HAEMOGLOBIN DECREASED14
GASTROINTESTINAL DISORDER14
DRUG EFFECT DECREASED14
DERMATITIS EXFOLIATIVE14
DERMATITIS ALLERGIC14
CHEST DISCOMFORT14
BALANCE DISORDER14
OSTEOARTHRITIS13
HEMIPLEGIA13
GASTRIC DISORDER13
GAIT DISTURBANCE13
ANGIOPATHY13
TREMOR12
TREATMENT NONCOMPLIANCE12
STRESS12
SOMNOLENCE12
SKIN ULCER12
RESPIRATORY DISORDER12
RASH PAPULAR12
PULMONARY OEDEMA12
MEMORY IMPAIRMENT12
LUNG DISORDER12
GASTRIC ULCER12
FLUID RETENTION12
DIFFICULTY IN WALKING12
CHRONIC OBSTRUCTIVE PULMONARY DISEASE12
BLOOD CREATININE INCREASED12
ANGIONEUROTIC OEDEMA12
TACHYCARDIA11
RASH PUSTULAR11
RASH MACULAR11
KNEE ARTHROPLASTY11
INFECTION11
HEART RATE IRREGULAR11
DIALYSIS11
CARDIO-RESPIRATORY ARREST11
BURNING SENSATION11
BLOOD GLUCOSE INCREASED11
ANAPHYLACTIC REACTION11
ALOPECIA11
VENTRICULAR HYPERTROPHY10
SPEECH DISORDER10
POST PROCEDURAL COMPLICATION10
PHOTOSENSITIVITY REACTION10
OSTEOPOROSIS10
NO ADVERSE EVENT10
NECK PAIN10
MEDICATION ERROR10
HEPATIC FAILURE10
HAEMATEMESIS10
GENERAL PHYSICAL HEALTH DETERIORATION10
DRY SKIN10
DRY MOUTH10
CARDIAC MURMUR10
BODY TEMPERATURE INCREASED10
ARTHROPATHY10
WHITE BLOOD CELL COUNT INCREASED9
ULCER HAEMORRHAGE9
TINNITUS9
STOMATITIS9
SKIN BURNING SENSATION9
RESPIRATORY ARREST9
RENAL IMPAIRMENT9
PSORIASIS9
OEDEMA9
MYOCARDIAL ISCHAEMIA9
INTERVERTEBRAL DISC PROTRUSION9
HEART INJURY9
EYE SWELLING9
COUGH9
CIRCULATORY COLLAPSE9
CARDIOMYOPATHY9
CARDIOMEGALY9
BRONCHOSPASM9
BRAIN DAMAGE9
ARTERIOSCLEROSIS CORONARY ARTERY9
ABDOMINAL DISTENSION9
ABDOMINAL DISCOMFORT9
SUDDEN DEATH8
SUDDEN CARDIAC DEATH8
SINUSITIS8
SCAB8
PHARMACEUTICAL PRODUCT COMPLAINT8
OCULAR VASCULAR DISORDER8
LACUNAR INFARCTION8
JOINT SWELLING8
HIATUS HERNIA8
HALLUCINATION8
HAEMATOCHEZIA8
FAECES DISCOLOURED8
EYE DISORDER8
DUODENAL ULCER8
CELLULITIS8
BURSITIS8
ACUTE CORONARY SYNDROME8
VISUAL FIELD DEFECT7
VIRAL INFECTION7
VERTIGO7
VASCULITIS7
URINARY TRACT INFECTION7
THROMBOCYTOPENIA7
THROAT TIGHTNESS7
SPINAL OSTEOARTHRITIS7
SLEEP DISORDER7
SLEEP APNOEA SYNDROME7
PULMONARY HYPERTENSION7
ORAL MUCOSAL BLISTERING7
MUSCULOSKELETAL STIFFNESS7
MUSCULAR WEAKNESS7
MUSCLE CRAMP7
MITRAL VALVE INCOMPETENCE7
INFLUENZA LIKE ILLNESS7
HYPERTENSIVE CRISIS7
HYPERKALAEMIA7
GASTRITIS EROSIVE7
FLUSHING7
EJECTION FRACTION DECREASED7
CONSTIPATION7
COMA7
COGNITIVE DISORDER7
CAROTID ARTERY STENOSIS7
CARDIAC VALVE DISEASE7
BIPOLAR DISORDER7
APHASIA7
VENTRICULAR EXTRASYSTOLES6
URTICARIA GENERALISED6
UPPER GASTROINTESTINAL HAEMORRHAGE6
ULCER6
TRICUSPID VALVE INCOMPETENCE6
SURGERY6
SUICIDAL IDEATION6
SPINAL COLUMN STENOSIS6
SKIN HAEMORRHAGE6
SKIN DESQUAMATION6
ROSACEA6
RETINAL HAEMORRHAGE6
RECTAL HAEMORRHAGE6
PROCEDURAL COMPLICATION6
POST-TRAUMATIC STRESS DISORDER6
POLLAKIURIA6
PLEURAL EFFUSION6
PHARYNGOLARYNGEAL PAIN6
PERIPHERAL VASCULAR DISORDER6
OEDEMA MOUTH6
MOUTH ULCERATION6
LIVER FUNCTION TEST ABNORMAL6
LICHEN PLANUS6
INTERNATIONAL NORMALISED RATIO INCREASED6
INFLUENZA6
INCORRECT DOSE ADMINISTERED6
IMPAIRED DRIVING ABILITY6
HYPERLIPIDAEMIA6
HYPERCHOLESTEROLAEMIA6
HIP ARTHROPLASTY6
HEPATOCELLULAR DAMAGE6
HEPATITIS6
HEART RATE DECREASED6
GASTRITIS6
EMOTIONAL DISTRESS6
DYSPNOEA EXERTIONAL6
DYSARTHRIA6
DRUG INTOLERANCE6
DERMATITIS BULLOUS6
BRONCHITIS6
BODY HEIGHT DECREASED6
WHEEZING5
WALKING AID USER5
VISUAL ACUITY REDUCED5
UPPER RESPIRATORY TRACT INFECTION5
THERAPY NON-RESPONDER5
SWOLLEN TONGUE5
SUPRAVENTRICULAR EXTRASYSTOLES5
STAPHYLOCOCCAL INFECTION5
ROTATOR CUFF SYNDROME5
RHEUMATOID ARTHRITIS5
RETINAL VEIN OCCLUSION5
RASH VESICULAR5
PURPURA5
PRURITUS GENERALISED5
PLATELET COUNT DECREASED5
PETECHIAE5
NODULE5
NO ADVERSE EFFECT5
NERVOUS SYSTEM DISORDER5
NEPHROLITHIASIS5
NASOPHARYNGITIS5
MUSCULOSKELETAL DISCOMFORT5
MIGRAINE5
JAUNDICE5
IMPAIRED WORK ABILITY5
HAEMORRHAGIC STROKE5
HAEMODIALYSIS5
HAEMATOCRIT DECREASED5
FLATULENCE5
EXTRASYSTOLES5
EPISTAXIS5
EMBOLISM5
EAR PAIN5
DISORIENTATION5
DEMENTIA5
DEAFNESS5
COLD SWEAT5
COAGULOPATHY5
CEREBRAL THROMBOSIS5
CEREBRAL ISCHAEMIA5
CEREBRAL HAEMORRHAGE5
CATARACT5
CARDIOGENIC SHOCK5
C-REACTIVE PROTEIN INCREASED5
BONE DISORDER5
BLOOD UREA INCREASED5
BLOOD POTASSIUM DECREASED5
BACK DISORDER5
AORTIC VALVE INCOMPETENCE5
ANURIA5
ANOREXIA5
ANAPHYLACTIC SHOCK5
ALANINE AMINOTRANSFERASE INCREASED5
ACTIVITIES OF DAILY LIVING IMPAIRED5
ACTINIC KERATOSIS5
VENTRICULAR FIBRILLATION4
VASCULAR OCCLUSION4
VAGINAL HAEMORRHAGE4
TONGUE ULCERATION4
TENDERNESS4
SPINAL COMPRESSION FRACTURE4
SKIN HYPERPIGMENTATION4
SHOULDER PAIN4
SENSATION OF FOREIGN BODY4
SEBORRHOEIC KERATOSIS4
RETINAL VASCULAR OCCLUSION4
RESTLESSNESS4
REFUSAL OF TREATMENT BY PATIENT4
RED BLOOD CELL COUNT DECREASED4
PULMONARY THROMBOSIS4
PULMONARY CONGESTION4
PROTHROMBIN TIME PROLONGED4
POLYTRAUMATISM4
PITTING OEDEMA4
PHARYNGEAL OEDEMA4
ORAL INTAKE REDUCED4
OESOPHAGITIS4
OBESITY4
NIGHTMARE4
NEUROPATHY4
NEPHRITIS INTERSTITIAL4
MULTI-ORGAN FAILURE4
MUCOUS MEMBRANE DISORDER4
MONOPLEGIA4
MITRAL VALVE PROLAPSE4
METABOLIC ACIDOSIS4
LYMPHOMA4
LOWER LIMB FRACTURE4
LIVER DISORDER4
LIMB INJURY4
LEUKOCYTOSIS4
LEUKOCYTOCLASTIC VASCULITIS4
KIDNEY INFECTION4
ISCHAEMIC CEREBRAL INFARCTION4
INTERVERTEBRAL DISC DISORDER4
INFLAMMATION4
INCONTINENCE4
HYPOXIA4
HYPOTHYROIDISM4
HYPONATRAEMIA4
HIP FRACTURE4
HERPES ZOSTER4
GASTRIC ULCER HAEMORRHAGE4
GASTRIC HAEMORRHAGE4
FURUNCLE4
FUNGAL INFECTION4
FIBROMYALGIA4
FACIAL PALSY4
FACE OEDEMA4
ELECTROCARDIOGRAM ABNORMAL4
DYSGEUSIA4
DISTURBANCE IN ATTENTION4
DISEASE RECURRENCE4
DISCOMFORT4
DILATATION ATRIAL4
DERMATITIS CONTACT4
DECREASED APPETITE4
DEAFNESS UNILATERAL4
COLONIC POLYP4
CARPAL TUNNEL SYNDROME4
BUNDLE BRANCH BLOCK RIGHT4
BREAST CANCER4
BRADYCARDIA4
BLOOD URINE PRESENT4
BLOOD TRIGLYCERIDES INCREASED4
BLOOD PRESSURE FLUCTUATION4
BLOOD PRESSURE DECREASED4
BLOOD LACTATE DEHYDROGENASE INCREASED4
BASAL CELL CARCINOMA4
ATROPHY4
ASPARTATE AMINOTRANSFERASE INCREASED4
ANGINA UNSTABLE4
ANEURYSM4
ACUTE RESPIRATORY FAILURE4
ACNE4
ABNORMAL DREAMS4
VASCULAR INJURY3
VASCULAR BYPASS GRAFT3
URINE OUTPUT DECREASED3
URINARY INCONTINENCE3
UPPER LIMB FRACTURE3
TONGUE OEDEMA3
THYROID DISORDER3
TENDON INJURY3
SYSTEMIC LUPUS ERYTHEMATOSUS3
SUPRAVENTRICULAR TACHYCARDIA3
STENT PLACEMENT3
SPINAL DISORDER3
SKIN NECROSIS3
SKIN IRRITATION3
SKIN GRAFT3
SINUS BRADYCARDIA3
SILENT MYOCARDIAL INFARCTION3
SEPTIC SHOCK3
SENSORY DISTURBANCE3
ROAD TRAFFIC ACCIDENT3
RESTLESS LEGS SYNDROME3
RASH SCALY3
RASH MORBILLIFORM3
PROCEDURAL PAIN3
PNEUMONIA ASPIRATION3
PERIORBITAL HAEMATOMA3
PALLOR3
OVERDOSE3
ORTHOSTATIC HYPOTENSION3
OEDEMA MUCOSAL3
OBSTRUCTIVE AIRWAYS DISORDER3
NIGHT SWEATS3
NEUROPATHY PERIPHERAL3
NEURODERMATITIS3
NEURITIS3
NERVE INJURY3
NEPHROTIC SYNDROME3
MUSCULOSKELETAL PAIN3
MUSCULOSKELETAL CHEST PAIN3
MUCOSAL HAEMORRHAGE3
MOBILITY DECREASED3
MASS3
LYMPHADENOPATHY3
LIP SWELLING3
LIP DRY3
JOINT SPRAIN3
JOINT RANGE OF MOTION DECREASED3
IRRITABLE BOWEL SYNDROME3
INTESTINAL FUNCTIONAL DISORDER3
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION3
HICCUPS3
HERNIA REPAIR3
HEART RATE ABNORMAL3
HAEMORRHAGE INTRACRANIAL3
HAEMOPTYSIS3
HAEMATURIA3
HAEMATOMA3
GENERALISED OEDEMA3
GASTROINTESTINAL NECROSIS3
FEELING HOT3
FEELING COLD3
FEAR3
FACIAL PARESIS3
EXOSTOSIS3
EMPHYSEMA3
ECCHYMOSIS3
DYSURIA3
DUODENAL ULCER HAEMORRHAGE3
DIABETES MELLITUS INADEQUATE CONTROL3
DECREASED ACTIVITY3
CYSTITIS3
CYST3
COORDINATION ABNORMAL3
CHOLESTASIS3
CHOLELITHIASIS3
CEREBRAL ARTERY OCCLUSION3
CEREBELLAR INFARCTION3
CAROTID ARTERY OCCLUSION3
BREAST PAIN3
BLOOD PRESSURE SYSTOLIC INCREASED3
BLOOD PRESSURE INADEQUATELY CONTROLLED3
BLOOD PRESSURE ABNORMAL3
BLOOD POTASSIUM INCREASED3
BLOOD HOMOCYSTEINE INCREASED3
BLOOD CREATINE INCREASED3
BLOOD BLISTER3
AZOTAEMIA3
ATRIAL FLUTTER3
ATELECTASIS3
ASCITES3
AORTIC VALVE DISEASE3
AORTIC STENOSIS3
ANOXIC ENCEPHALOPATHY3
AGEUSIA3
ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS3
ABSCESS3
ABASIA3
WHITE BLOOD CELL COUNT DECREASED2
VISUAL IMPAIRMENT2
VENTRICULAR TACHYCARDIA2
VENOUS THROMBOSIS2
VEIN DISORDER2
VASCULITIC RASH2
VARICOSE VEIN2
URINARY TRACT DISORDER2
ULTRASOUND DOPPLER ABNORMAL2
TIBIA FRACTURE2
THROAT IRRITATION2
THINKING ABNORMAL2
THALAMIC INFARCTION2
TENDONITIS2
TENDON RUPTURE2
TENDON DISORDER2
SYNOVIAL CYST2
SURGICAL PROCEDURE REPEATED2
SUBARACHNOID HAEMORRHAGE2
STUPOR2
SPINAL OPERATION2
SPINAL FRACTURE2
SKIN WRINKLING2
SKIN OEDEMA2
SKIN NODULE2
SKIN LACERATION2
SKIN DEPIGMENTATION2
SKIN CHAPPED2
SKIN CANCER2
SHOULDER ARTHROPLASTY2
SEXUAL DYSFUNCTION2
SENSATION OF HEAVINESS2
SELF-MEDICATION2
SELF ESTEEM DECREASED2
SEBORRHOEIC DERMATITIS2
SCRATCH2
SCOTOMA2
SCLERODERMA2
SCHIZOPHRENIA2
RIB FRACTURE2
RETINAL ARTERY OCCLUSION2
RESPIRATORY RATE INCREASED2
RESPIRATORY DISTRESS2
RENAL PAIN2
RENAL FAILURE CHRONIC2
RENAL ARTERY OCCLUSION2
REFLUX OESOPHAGITIS2
RED BLOOD CELL SEDIMENTATION RATE INCREASED2
PULSE ABSENT2
PULMONARY FIBROSIS2
PSEUDOMONAS INFECTION2
PROTHROMBIN TIME SHORTENED2
PROTEIN TOTAL DECREASED2
PROSTATIC SPECIFIC ANTIGEN INCREASED2
PRECANCEROUS SKIN LESION2
POSTOPERATIVE WOUND INFECTION2
POSTOPERATIVE THROMBOSIS2
POLYP2
PLANTAR FASCIITIS2
PITYRIASIS RUBRA PILARIS2
PIGMENTATION DISORDER2
PHYSICAL DISABILITY2
PHARYNGITIS2
PETIT MAL EPILEPSY2
PERIPHERAL COLDNESS2
PERICARDIAL EFFUSION2
PEPTIC ULCER2
PELVIC PAIN2
PELVIC FRACTURE2
PARKINSON'S DISEASE2
PARALYSIS2
PANCYTOPENIA2
PANCREATITIS2
PAIN IN JAW2
OSTEOMYELITIS2
OROPHARYNGEAL SWELLING2
ORAL PAIN2
OPTIC ISCHAEMIC NEUROPATHY2
OPEN WOUND2
OESOPHAGEAL ULCER2
ODYNOPHAGIA2
OBSESSIVE-COMPULSIVE DISORDER2
NUCLEAR MAGNETIC RESONANCE IMAGING ABNORMAL2
NODAL OSTEOARTHRITIS2
NO ADVERSE DRUG EFFECT2
NEUTROPHIL COUNT INCREASED2
NEUTROPENIA2
NERVE COMPRESSION2
NEPHRECTOMY2
NECROSIS2
NASAL DISCOMFORT2
MYOSITIS2
MUSCLE TWITCHING2
MUSCLE RIGIDITY2
MUSCLE INJURY2
MUSCLE DISORDER2
MUSCLE ATROPHY2
MULTIPLE SCLEROSIS2
MULTIPLE INJURIES2
MOVEMENT DISORDER2
MOUTH HAEMORRHAGE2
METASTATIC NEOPLASM2
MENTAL STATUS CHANGES2
MENTAL IMPAIRMENT2
MENISCUS LESION2
MARKEDLY REDUCED DIETARY INTAKE2
MALIGNANT MELANOMA2
MALIGNANT HYPERTENSION2
MAJOR DEPRESSION2
MACULAR DEGENERATION2
LYMPHOPENIA2
LUPUS-LIKE SYNDROME2
LOWER RESPIRATORY TRACT INFECTION2
LOW DENSITY LIPOPROTEIN INCREASED2
LOSS OF LIBIDO2
LOCALISED INFECTION2
LOCAL SWELLING2
LIBIDO DECREASED2
LEUKOPENIA2
LEG AMPUTATION2
LEFT VENTRICULAR FAILURE2
LARGE INTESTINE PERFORATION2
LARGE INTESTINAL ULCER2
LACTIC ACIDOSIS2
LACRIMATION INCREASED2
LACERATION2
JOINT STIFFNESS2
JOINT EFFUSION2
ISCHAEMIA2
INTRACRANIAL ANEURYSM2
INTRACARDIAC THROMBUS2
INTERVERTEBRAL DISC DEGENERATION2
INFARCTION2
INCREASED UPPER AIRWAY SECRETION2
INCISION SITE COMPLICATION2
INADEQUATE ANALGESIA2
IMPETIGO2
IMMUNE SYSTEM DISORDER2
ILL-DEFINED DISORDER2
HYPOVOLAEMIA2
HYPOKINESIA2
HYPOGLYCAEMIA2
HYPOAESTHESIA ORAL2
HYPOACUSIS2
HYPERTROPHY BREAST2
HYPERTHYROIDISM2
HYPERGLYCAEMIA2
HYPERAESTHESIA2
HYDROCEPHALUS2
HOT FLUSH2
HOARSENESS2
HERNIA2
HEPATIC STEATOSIS2
HEPATIC FUNCTION ABNORMAL2
HEPATIC ENZYME INCREASED2
HEPATIC CIRRHOSIS2
HEAT RASH2
HAEMORRHOIDS2
GUTTATE PSORIASIS2
GRAND MAL CONVULSION2
GLOMERULONEPHRITIS2
GINGIVAL PAIN2
GINGIVAL DISORDER2
GASTROINTESTINAL ULCER HAEMORRHAGE2
GAMMA-GLUTAMYLTRANSFERASE INCREASED2
GALLOP RHYTHM PRESENT2
GALLBLADDER DISORDER2
FRUSTRATION2
FREQUENT BOWEL MOVEMENTS2
FRACTURE2
FOOT FRACTURE2
FLANK PAIN2
FEMUR FRACTURE2
FEELING JITTERY2
EYE PAIN2
EYE OEDEMA2
EXPRESSIVE LANGUAGE DISORDER2
EXCORIATION2
ERYTHEMA NODOSUM2
EMOTIONAL DISORDER2
EMBOLIC STROKE2
ECONOMIC PROBLEM2
ECHOCARDIOGRAM ABNORMAL2
DYSPHONIA2
DYSHIDROSIS2
DYSGRAPHIA2
DRY THROAT2
DRUG TOXICITY2
DRUG EXPOSURE DURING PREGNANCY2
DISSEMINATED INTRAVASCULAR COAGULATION2
DIASTOLIC DYSFUNCTION2
DIARRHOEA HAEMORRHAGIC2
DIABETES MELLITUS NON-INSULIN-DEPENDENT2
DIABETES MELLITUS INSULIN-DEPENDENT2
DERMATITIS EXFOLIATIVE GENERALISED2
DEPRESSED LEVEL OF CONSCIOUSNESS2
DEMYELINATION2
DEMENTIA ALZHEIMER'S TYPE2
CYANOSIS2
CRYING2
CROHN'S DISEASE2
COSTOCHONDRITIS2
CORONARY ARTERY SURGERY2
CORONARY ARTERY INSUFFICIENCY2
CORONARY ARTERIAL STENT INSERTION2
CONDUCTION DISORDER2
COMPUTERISED TOMOGRAM ABNORMAL2
COMPLEX REGIONAL PAIN SYNDROME2
COLONIC HAEMORRHAGE2
CHROMATURIA2
CHOLECYSTITIS ACUTE2
CHOLECYSTITIS2
CHOKING2
CEREBRAL DISORDER2
CATHETER RELATED INFECTION2
CARDIAC STRESS TEST ABNORMAL2
CARDIAC ENZYMES INCREASED2
CANDIDIASIS2
BRONCHOPNEUMONIA2
BREAST TENDERNESS2
BRAIN OEDEMA2
BRAIN DEATH2
BONE PAIN2
BLOOD TEST ABNORMAL2
BLOOD SODIUM DECREASED2
BLOOD PRESSURE SYSTOLIC DECREASED2
BLOOD PRESSURE IMMEASURABLE2
BLOOD DISORDER2
BLOOD CREATINE PHOSPHOKINASE INCREASED2
BLINDNESS TRANSIENT2
BENIGN PROSTATIC HYPERPLASIA2
BEDRIDDEN2
BACK INJURY2
AURICULAR SWELLING2
ATRIOVENTRICULAR BLOCK SECOND DEGREE2
ATRIOVENTRICULAR BLOCK COMPLETE2
ATRIOVENTRICULAR BLOCK2
ATHEROSCLEROSIS2
ATAXIA2
ARTHROSCOPY2
ARTERIAL INJURY2
ARTERIAL HAEMORRHAGE2
ARTERIAL DISORDER2
APHTHOUS STOMATITIS2
APHONIA2
AORTIC RUPTURE2
AORTIC OCCLUSION2
AORTIC ANEURYSM2
ANTINUCLEAR ANTIBODY POSITIVE2
ANKLE OPERATION2
ANKLE FRACTURE2
ALCOHOL USE2
ADVERSE EVENT2
ABDOMINAL HERNIA2
WRONG TECHNIQUE IN DRUG USAGE PROCESS1
WRIST SURGERY1
WRIST FRACTURE1
WOUND SECRETION1
WOUND INFECTION STAPHYLOCOCCAL1
WOUND INFECTION1
WOUND COMPLICATION1
WOUND1
WHOLE BLOOD TRANSFUSION1
WHITE BLOOD CELLS URINE POSITIVE1
WHEELCHAIR USER1
WEIGHT LOSS POOR1
WEIGHT FLUCTUATION1
VULVOVAGINAL DISCOMFORT1
VULVAL OEDEMA1
VOLUME BLOOD DECREASED1
VOCAL CORD POLYP1
VITAMIN B12 DEFICIENCY1
VENOUS STENOSIS1
VENOUS OCCLUSION1
VENOUS INSUFFICIENCY1
VASCULAR RUPTURE1
VASCULAR PSEUDOANEURYSM1
VASCULAR OPERATION1
VASCULAR GRAFT OCCLUSION1
VASCULAR BYPASS DYSFUNCTION1
VARICELLA1
VAGINAL ODOUR1
VAGINAL DISORDER1
VAGINAL CANDIDIASIS1
URINE ODOUR ABNORMAL1
URINE AMPHETAMINE POSITIVE1
URINARY BLADDER HAEMORRHAGE1
UNDERWEIGHT1
TYPE III IMMUNE COMPLEX MEDIATED REACTION1
TUBULOINTERSTITIAL NEPHRITIS1
TUBERCULOSIS1
TRIPLE VESSEL BYPASS GRAFT1
TRIGGER FINGER1
TRICUSPID VALVE DISEASE1
TRICHORRHEXIS1
TRANSPLANT REJECTION1
TRANSFUSION REACTION1
TRANSAMINASES INCREASED1
TOXIC SKIN ERUPTION1
TOXIC SHOCK SYNDROME1
TOOTHACHE1
TOOTH INFECTION1
TOOTH DISORDER1
TONSILLAR DISORDER1
TONGUE INJURY1
TONGUE DISORDER1
TONGUE BLISTERING1
TOE AMPUTATION1
TINEA CRURIS1
THYROIDITIS1
THYROID MASS1
THROMBOPHLEBITIS1
THERAPEUTIC RESPONSE UNEXPECTED1
THERAPEUTIC RESPONSE INCREASED1
THERAPEUTIC RESPONSE DECREASED1
TETANY1
TALIPES1
TACHYPNOEA1
SYNCOPE VASOVAGAL1
SUTURE RELATED COMPLICATION1
SUTURE LINE INFECTION1
SUICIDE ATTEMPT1
SUDDEN HEARING LOSS1
SUBCUTANEOUS HAEMATOMA1
STRESS URINARY INCONTINENCE1
STRESS INCONTINENCE1
STRESS FRACTURE1
STREPTOCOCCAL INFECTION1
STRABISMUS1
STENT OCCLUSION1
STASIS DERMATITIS1
STAPHYLOCOCCAL SEPSIS1
STAPHYLOCOCCAL SCALDED SKIN SYNDROME1
STAPHYLOCOCCAL BACTERAEMIA1
SPUTUM DISCOLOURED1
SPONDYLOLISTHESIS1
SPONDYLITIS1
SPLENOMEGALY1
SPLENIC RUPTURE1
SPLEEN CONGESTION1
SPINAL CORD INJURY1
SOLAR ELASTOSIS1
SODIUM RETENTION1
SNEEZING1
SMOKER1
SMALL INTESTINE ULCER1
SMALL INTESTINAL PERFORATION1
SMALL INTESTINAL OBSTRUCTION1
SMALL CELL LUNG CANCER STAGE UNSPECIFIED1
SLUGGISHNESS1
SKULL FRACTURE1
SKIN WARM1
SKIN TIGHTNESS1
SKIN TEST POSITIVE1
SKIN SWELLING1
SKIN STRIAE1
SKIN PAPILLOMA1
SKIN ODOUR ABNORMAL1
SKIN INJURY1
SKIN INFECTION1
SKIN HYPOPIGMENTATION1
SKIN HYPERTROPHY1
SKIN BACTERIAL INFECTION1
SJOGREN'S SYNDROME1
SINUS TACHYCARDIA1
SINUS OPERATION1
SINUS DISORDER1
SINUS CONGESTION1
SINUS ARRHYTHMIA1
SICK SINUS SYNDROME1
SHOULDER OPERATION1
SHOCK1
SERUM SICKNESS1
SEPTIC RASH1
SENSORY LOSS1
SENSATION OF PRESSURE1
SEBORRHOEA1
SEASONAL AFFECTIVE DISORDER1
SCREAMING1
SCIATICA1
SALMONELLOSIS1
SALIVARY HYPERSECRETION1
SALIVARY GLAND ENLARGEMENT1
RUPTURED CEREBRAL ANEURYSM1
RIGHT VENTRICULAR FAILURE1
RHINITIS ALLERGIC1
RHABDOMYOLYSIS1
RETINAL VEIN THROMBOSIS1
RETINAL TEAR1
RETINAL INFARCTION1
RETINAL DETACHMENT1
RETINAL ARTERY THROMBOSIS1
RETCHING1
RESPIRATORY TRACT INFECTION1
RESPIRATORY TRACT CONGESTION1
RESPIRATORY DEPRESSION1
RESPIRATION ABNORMAL1
RENAL TUBULAR NECROSIS1
RENAL HAEMORRHAGE1
RENAL CELL CARCINOMA STAGE UNSPECIFIED1
RENAL ARTERY STENOSIS1
RENAL ANEURYSM1
REFUSAL OF TREATMENT BY RELATIVE1
RECURRING SKIN BOILS1
RECTOCELE1
RECTAL ULCER HAEMORRHAGE1
RECTAL TENESMUS1
RECTAL CRAMPS1
REACTION TO MEDICAL AGENT PRESERVATIVES1
REACTION TO COLOURING1
RASH FOLLICULAR1
RADIUS FRACTURE1
RADICULOPATHY1
QUADRIPLEGIA1
PUPIL FIXED1
PULMONARY MASS1
PULMONARY INFARCTION1
PULMONARY COCCIDIOIDES1
PULMONARY ARTERY ANEURYSM1
PSEUDOMONAL BACTERAEMIA1
PROTHROMBIN LEVEL ABNORMAL1
PROTEIN S DEFICIENCY1
PROSTATE CANCER1
PRODUCTIVE COUGH1
POSTURE ABNORMAL1
POSTOPERATIVE INFECTION1
POSTOPERATIVE ABSCESS1
POSTNASAL DRIP1
POST THROMBOTIC SYNDROME1
POST PROCEDURAL PAIN1
POST PROCEDURAL NAUSEA1
POST PROCEDURAL HAEMORRHAGE1
POST INFLAMMATORY PIGMENTATION CHANGE1
PORTAL HYPERTENSION1
PORPHYRIA1
POOR VENOUS ACCESS1
POOR QUALITY SLEEP1
POOR QUALITY DRUG ADMINISTERED1
POOR PERIPHERAL CIRCULATION1
POLYURIA1
POLYP COLORECTAL1
POLYNEUROPATHY1
POLYMYALGIA1
POLYARTHRITIS1
POISONING1
PNEUMOTHORAX1
PNEUMONITIS1
PNEUMATOSIS INTESTINALIS1
PLEURISY1
PLATELET AGGREGATION1
PITYRIASIS ROSEA1
PIGMENTED NAEVUS1
PHOTOSENSITIVE RASH1
PHOBIA1
PERSONALITY CHANGE1
PERONEAL NERVE PALSY1
PERNICIOUS ANAEMIA1
PERIPHERAL NERVE DECOMPRESSION1
PERICARDITIS1
PERIARTHRITIS1
PEPTIC ULCER PERFORATION1
PEPTIC ULCER HAEMORRHAGE1
PENIS DISORDER1
PENILE BLISTER1
PEMPHIGOID1
PATELLA FRACTURE1
PARTNER STRESS1
PARESIS1
PARANOIA1
PANCREATITIS CHRONIC1
PANCREATIC OPERATION1
PANCREATIC CARCINOMA1
PALATAL DISORDER1
PAIN OF SKIN1
OVARIAN ENLARGEMENT1
OVARIAN DISORDER1
OVARIAN CYST1
OSTEOPENIA1
OSTECTOMY1
ORTHOPNOEA1
OROPHARYNGEAL PAIN1
ORAL SOFT TISSUE DISORDER1
ORAL MUCOSAL DISORDER1
ORAL DISCOMFORT1
OPPORTUNISTIC INFECTION1
ONYCHORRHEXIS1
OESTROGEN RECEPTOR ASSAY POSITIVE1
OESOPHAGITIS ULCERATIVE1
OESOPHAGEAL SPASM1
OESOPHAGEAL OBSTRUCTION1
OESOPHAGEAL DISORDER1
OESOPHAGEAL DILATION PROCEDURE1
OESOPHAGEAL DILATATION1
OESOPHAGEAL CANDIDIASIS1
OCULAR HYPERAEMIA1
OCCULT BLOOD POSITIVE1
NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL1
NON-HODGKIN'S LYMPHOMA1
NON-CARDIOGENIC PULMONARY OEDEMA1
NODAL RHYTHM1
NO THERAPEUTIC RESPONSE1
NIPPLE DISORDER1
NEUTROPHILIA1
NEUTROPHIL COUNT DECREASED1
NEUROPATHIC PAIN1
NEUROMA1
NEUROLOGICAL SYMPTOM1
NEURALGIA1
NEPHROSCLEROSIS1
NEPHROPATHY TOXIC1
NEOPLASM SKIN1
NEOPLASM PROGRESSION1
NEOPLASM MALIGNANT1
NEOPLASM1
NECK INJURY1
NASAL ULCER1
NASAL MUCOSAL DISORDER1
NASAL DISORDER1
NASAL CONGESTION1
NAIL DISORDER1
NAIL DISCOLOURATION1
MYOPIA1
MYOPATHY1
MYOCARDIAL FIBROSIS1
MYCOSIS FUNGOIDES1
MUSCULOSKELETAL DISORDER1
MUSCLE STRAIN1
MUSCLE RUPTURE1
MULTIPLE FRACTURES1
MULTIPLE ALLERGIES1
MOUTH PLAQUE1
MOUTH CYST1
MORPHOEA1
MONOCYTE COUNT INCREASED1
MIXED CONNECTIVE TISSUE DISEASE1
MITRAL VALVE DISEASE1
MIOSIS1
MICTURITION URGENCY1
MICROANGIOPATHY1
METASTASIS1
METASTASES TO BONE MARROW1
METABOLIC SYNDROME1
MENTAL DISORDER DUE TO A GENERAL MEDICAL CONDITION1
MENTAL DISORDER1
MENOPAUSE1
MENISCUS REMOVAL1
MENINGITIS1
MENIERE'S DISEASE1
MEDICAL DEVICE COMPLICATION1
MALNUTRITION1
MACULAR HOLE1
LYMPHOMATOID PAPULOSIS1
LYMPHOEDEMA1
LYMPHOCYTE PERCENTAGE INCREASED1
LYMPHOCYTE COUNT DECREASED1
LUNG TRANSPLANT1
LUNG OPERATION1
LUNG INFILTRATION1
LUNG INFECTION1
LUMBAR RADICULOPATHY1
LOWER GASTROINTESTINAL HAEMORRHAGE1
LOW DENSITY LIPOPROTEIN DECREASED1
LOOSE STOOLS1
LOCALISED OEDEMA1
LOBAR PNEUMONIA1
LIVING IN RESIDENTIAL INSTITUTION1
LIVER ABSCESS1
LIPOMA EXCISION1
LIPOMA1
LIPASE INCREASED1
LIP ULCERATION1
LIMB DISCOMFORT1
LIGAMENT INJURY1
LICHENOID KERATOSIS1
LICHENIFICATION1
LETHARGY1
LEFT VENTRICULAR HYPERTROPHY1
LEFT VENTRICULAR DYSFUNCTION1
LATEX ALLERGY1
LARYNGEAL OEDEMA1
LARYNGEAL DISORDER1
LABYRINTHITIS1
LABORATORY TEST INTERFERENCE1
LABORATORY TEST ABNORMAL1
KNEE OPERATION1
KNEE DEFORMITY1
KIDNEY SMALL1
KETOACIDOSIS1
JOINT LOCK1
JOINT INJURY1
JOINT DISLOCATION1
JOINT CREPITATION1
JOINT CONTRACTURE1
JAUNDICE CHOLESTATIC1
ISCHAEMIC CARDIOMYOPATHY1
IRON DEFICIENCY ANAEMIA1
IRON DEFICIENCY1
IODINE ALLERGY1
INTRACRANIAL HYPOTENSION1
INTRA-UTERINE DEATH1
INTRA-ABDOMINAL HAEMORRHAGE1
INTESTINAL ULCER1
INTESTINAL PERFORATION1
INTESTINAL OBSTRUCTION1
INTESTINAL ISCHAEMIA1
INTESTINAL HAEMORRHAGE1
INTERVERTEBRAL DISCITIS1
INTERVERTEBRAL DISC OPERATION1
INTERTRIGO1
INTERSTITIAL LUNG DISEASE1
INTERNATIONAL NORMALISED RATIO DECREASED1
INSULIN RESISTANT DIABETES1
INNER EAR DISORDER1
INGROWING NAIL1
INFECTED SKIN ULCER1
INDURATION1
INCREASED TENDENCY TO BRUISE1
INCOHERENT1
INCISIONAL DRAINAGE1
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION1
IMPRISONMENT1
IMPLANT SITE INFECTION1
IMPAIRED GASTRIC EMPTYING1
IMMUNOSUPPRESSION1
IMMUNODEFICIENCY1
IMMOBILE1
IDIOSYNCRATIC DRUG REACTION1
IDIOPATHIC THROMBOCYTOPENIC PURPURA1
HYPOVOLAEMIC SHOCK1
HYPOSMIA1
HYPOPHOSPHATAEMIA1
HYPOMAGNESAEMIA1
HYPOKALAEMIA1
HYPOCALCAEMIA1
HYPOALBUMINAEMIA1
HYPERTRIGLYCERIDAEMIA1
HYPERTENSIVE HEART DISEASE1
HYPERSOMNIA1
HYPERKERATOSIS1
HYPERHOMOCYSTEINAEMIA1
HYPERCALCAEMIA1
HYPERAEMIA1
HORMONE LEVEL ABNORMAL1
HIP SURGERY1
HIGH DENSITY LIPOPROTEIN DECREASED1
HERPES ZOSTER MULTI-DERMATOMAL1
HERPES VIRUS INFECTION1
HERPES SIMPLEX1
HERPES OESOPHAGITIS1
HEPATOMEGALY1
HEPATIC NEOPLASM MALIGNANT1
HEPATIC INFARCTION1
HEPATIC CYST1
HEPATIC ADENOMA1
HENOCH-SCHONLEIN PURPURA1
HEMIANOPIA1
HEART VALVE REPLACEMENT1
HEARING IMPAIRED1
HEAD INJURY1
HEAD BANGING1
HANGOVER1
HAND-FOOT-AND-MOUTH DISEASE1
HAND DERMATITIS1
HALLUCINATION, VISUAL1
HALLUCINATION, AUDITORY1
HAIR TEXTURE ABNORMAL1
HAIR GROWTH ABNORMAL1
HAEMORRHOIDAL HAEMORRHAGE1
HAEMOLYTIC ANAEMIA1
HAEMARTHROSIS1
GUILLAIN-BARRE SYNDROME1
GOUTY ARTHRITIS1
GLYCOSYLATED HAEMOGLOBIN INCREASED1
GLYCOSURIA1
GLUCOSE TOLERANCE IMPAIRED1
GLOSSODYNIA1
GLAUCOMA1
GINGIVAL SWELLING1
GINGIVAL RECESSION1
GINGIVAL BLEEDING1
GENITOURINARY TRACT INFECTION1
GENITAL PRURITUS FEMALE1
GENITAL DISORDER FEMALE1
GENERALISED ERYTHEMA1
GENERALISED ANXIETY DISORDER1
GAZE PALSY1
GASTROINTESTINAL ULCER PERFORATION1
GASTROINTESTINAL STROMAL TUMOUR1
GASTROINTESTINAL PERFORATION1
GASTROINTESTINAL PAIN1
GASTROINTESTINAL NEOPLASM1
GASTROINTESTINAL INFLAMMATION1
GASTROINTESTINAL INFECTION1
GASTROINTESTINAL EROSION1
GASTRIC PH INCREASED1
GASTRIC PH DECREASED1
GASTRIC MUCOSAL LESION1
GASTRIC DILATATION1
GANGRENE1
FUNGAL SKIN INFECTION1
FRACTURED SACRUM1
FORMICATION1
FOOT OPERATION1
FOOD ALLERGY1
FOLLICULITIS1
FOLATE DEFICIENCY1
FLUID INTAKE REDUCED1
FLAT FEET1
FLAT AFFECT1
FLASHBACK1
FINGER DEFORMITY1
FINGER AMPUTATION1
FIBRIN D DIMER INCREASED1
FEMALE GENITAL OPERATION1
FEELING HOT AND COLD1
FEAR OF DISEASE1
FEAR OF DEATH1
FAT NECROSIS1
FAMILY STRESS1
FALSE POSITIVE LABORATORY RESULT1
FAILURE TO THRIVE1
FAECES PALE1
FACIAL PAIN1
FACE INJURY1
FACE AND MOUTH X-RAY ABNORMAL1
EYELID FUNCTION DISORDER1
EYELID DISORDER1
EYE REDNESS1
EYE IRRITATION1
EYE HAEMORRHAGE1
EYE DISCHARGE1
EXPIRED DRUG ADMINISTERED1
EXFOLIATIVE RASH1
EXERCISE ELECTROCARDIOGRAM ABNORMAL1
ESCHERICHIA URINARY TRACT INFECTION1
ERYTHROPHAGOCYTOSIS1
ERYTHEMA OF EYELID1
ERYSIPELAS1
EROSIVE OESOPHAGITIS1
EROSIVE DUODENITIS1
ERECTILE DYSFUNCTION1
EPSTEIN-BARR VIRUS INFECTION1
EPIGLOTTIC OEDEMA1
EPIDERMOLYSIS1
EOSINOPHILIA1
EOSINOPHIL COUNT INCREASED1
EOSINOPHIL CATIONIC PROTEIN INCREASED1
ENDOMETRIOSIS1
ENDODONTIC PROCEDURE1
ENDOCARDITIS1
ENCEPHALOPATHY1
ELECTROLYTE IMBALANCE1
ELECTROCARDIOGRAM T WAVE ABNORMAL1
ELECTROCARDIOGRAM ST-T SEGMENT ABNORMAL1
ELECTROCARDIOGRAM ST SEGMENT ELEVATION1
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION1
ELECTROCARDIOGRAM POOR R-WAVE PROGRESSION1
ELECTROCARDIOGRAM CHANGE1
ECZEMA NUMMULAR1
ECZEMA ASTEATOTIC1
EATING DISORDER1
EAR INFECTION1
EAR HAEMORRHAGE1
EAR CONGESTION1
DYSSTASIA1
DYSPNOEA PAROXYSMAL NOCTURNAL1
DYSPNOEA EXACERBATED1
DYSPHEMIA1
DYSLIPIDAEMIA1
DYSAESTHESIA1
DUODENITIS1
DUODENAL ULCER PERFORATION1
DUODENAL STENOSIS1
DUODENAL SCARRING1
DUODENAL POLYP1
DRY EYE1
DRUG SCREEN FALSE POSITIVE1
DRUG DOSE OMISSION1
DRUG DISPENSING ERROR1
DRUG ABUSER1
DROOLING1
DIVERTICULUM INTESTINAL1
DIVERTICULITIS1
DIURETIC EFFECT1
DISEASE PROGRESSION1
DISEASE COMPLICATION1
DISABILITY1
DIPLOPIA1
DIPLEGIA1
DILATATION VENTRICULAR1
DIFFERENTIAL WHITE BLOOD CELL COUNT ABNORMAL1
DIAPHRAGMATIC DISORDER1
DIABETIC NEPHROPATHY1
DIABETIC KETOACIDOSIS1
DEVICE RELATED INFECTION1
DERMOID CYST1
DEPRESSED MOOD1
DECUBITUS ULCER1
DEAFNESS NEUROSENSORY1
CYSTOCELE1
CYST ASPIRATION1
CROSS SENSITIVITY REACTION1
CREST SYNDROME1
CREATININE RENAL CLEARANCE DECREASED1
CORONARY OSTIAL STENOSIS1
CORONARY ARTERY THROMBOSIS1
CORONARY ARTERY STENOSIS1
CORONARY ARTERY RESTENOSIS1
CORONARY ARTERY ATHEROSCLEROSIS1
CORONARY ANGIOPLASTY1
CORNEAL TRANSPLANT1
CORNEAL OEDEMA1
CONTRAINDICATION TO MEDICAL TREATMENT1
CONJUNCTIVAL HYPERAEMIA1
CONGESTIVE CARDIOMYOPATHY1
CONGENITAL MUSCULOSKELETAL ANOMALY1
COMPRESSION FRACTURE1
COMPLICATIONS OF TRANSPLANTED KIDNEY1
COMPLEX PARTIAL SEIZURES1
COLONOSCOPY1
COLLAPSE OF LUNG1
COLITIS ULCERATIVE1
COLITIS1
CLOSTRIDIUM DIFFICILE COLITIS1
CLOSTRIDIUM COLITIS1
CLOSTRIDIAL INFECTION1
CIRRHOSIS ALCOHOLIC1
CHRONIC FATIGUE SYNDROME1
CHOLINERGIC SYNDROME1
CHOLECYSTITIS INFECTIVE1
CHOLECYSTECTOMY1
CHEYNE-STOKES RESPIRATION1
CHEST X-RAY ABNORMAL1
CHEST WALL PAIN1
CHEST INJURY1
CHEMICAL INJURY1
CHEMICAL BURN OF SKIN1
CHAPPED LIPS1
CHANGE OF BOWEL HABIT1
CERUMEN IMPACTION1
CEREBROSPINAL FLUID LEAKAGE1
CEREBRAL ARTERY STENOSIS1
CEREBRAL ARTERY EMBOLISM1
CEREBRAL ARTERIOVENOUS MALFORMATION HAEMORRHAGIC1
CEREBELLAR HAEMORRHAGE1
CENTRAL PAIN SYNDROME1
CENTRAL NERVOUS SYSTEM LESION1
CATHETER SITE HAEMORRHAGE1
CATARACT OPERATION1
CATARACT DIABETIC1
CARTILAGE INJURY1
CAROTID BRUIT1
CAROTID ARTERY DISEASE1
CARDIOVASCULAR INSUFFICIENCY1
CARDIAC TAMPONADE1
CARDIAC PROCEDURE COMPLICATION1
CARDIAC PACEMAKER INSERTION1
CARDIAC OUTPUT INCREASED1
CARDIAC OPERATION1
CARDIAC MONITORING ABNORMAL1
CARDIAC FLUTTER1
CARDIAC ANEURYSM1
CARBUNCLE1
BURNING SENSATION MUCOSAL1
BUNDLE BRANCH BLOCK LEFT1
BRUCELLOSIS1
BRONCHIOLOALVEOLAR CARCINOMA1
BREATH SOUNDS ABNORMAL1
BREATH ODOUR1
BREAST SWELLING1
BREAST CANCER METASTATIC1
BRAIN STEM SYNDROME1
BRAIN NEOPLASM1
BRAIN INJURY1
BRAIN CANCER METASTATIC1
BRADYPHRENIA1
BOWEL MOVEMENT IRREGULARITY1
BONE MARROW DEPRESSION1
BONE GRAFT1
BONE DENSITY DECREASED1
BODY TINEA1
BLOOD URINE1
BLOOD THYROID STIMULATING HORMONE INCREASED1
BLOOD SODIUM INCREASED1
BLOOD PRESSURE DIASTOLIC DECREASED1
BLOOD PRESSURE DIASTOLIC1
BLOOD PARATHYROID HORMONE INCREASED1
BLOOD MAGNESIUM DECREASED1
BLOOD KETONE BODY1
BLOOD GLUCOSE DECREASED1
BLOOD GLUCOSE ABNORMAL1
BLOOD FIBRINOGEN INCREASED1
BLOOD CREATININE ABNORMAL1
BLOOD CALCIUM INCREASED1
BLOOD BILIRUBIN INCREASED1
BLOOD ALKALINE PHOSPHATASE INCREASED1
BLOOD ALCOHOL1
BLADDER PROLAPSE1
BLADDER DISORDER1
BLADDER DISCOMFORT1
BITE1
BIPOLAR I DISORDER1
BIOPSY SKIN ABNORMAL1
BILIARY COLIC1
BENIGN NEOPLASM OF SKIN1
BENIGN INTRACRANIAL HYPERTENSION1
BACTERIAL INFECTION1
AUTOIMMUNE HEPATITIS1
AURA1
ATTENTION DEFICIT/HYPERACTIVITY DISORDER1
ATRIOVENTRICULAR BLOCK FIRST DEGREE1
ATRIAL THROMBOSIS1
ARTERIOVENOUS MALFORMATION1
ARTERIOSPASM CORONARY1
ARTERIAL STENOSIS1
ARTERIAL RUPTURE1
ARTERIAL REPAIR1
ARRHYTHMIA SUPRAVENTRICULAR1
APPLICATION SITE IRRITATION1
APPLICATION SITE BLEEDING1
APPETITE DISORDER1
APPENDICECTOMY1
APOLIPOPROTEIN INCREASED1
APNOEIC ATTACK1
APLASTIC ANAEMIA1
AORTIC VALVE REPLACEMENT1
AORTIC INJURY1
AORTIC DISORDER1
AORTIC DILATATION1
ANXIETY DISORDER1
ANTISOCIAL BEHAVIOUR1
ANGIOPLASTY1
ANGIOEDEMA1
ANEURYSM RUPTURED1
ANAESTHETIC COMPLICATION1
ANAEMIA HAEMOLYTIC AUTOIMMUNE1
AMPUTATION1
ALVEOLITIS1
AKINESIA1
AGONAL RHYTHM1
AGITATION1
AFFECTIVE DISORDER1
ADNEXA UTERI MASS1
ADHESION1
ADENOCARCINOMA1
ACUTE SINUSITIS1
ACUTE RIGHT VENTRICULAR FAILURE1
ACUTE RESPIRATORY DISTRESS SYNDROME1
ACUTE PULMONARY OEDEMA1
ACUTE PRERENAL FAILURE1
ACUTE LEFT VENTRICULAR FAILURE1
ACUTE FEBRILE NEUTROPHILIC DERMATOSIS1
ACQUIRED OESOPHAGEAL WEB1
ACIDOSIS1
ACCIDENT1
ACARODERMATITIS1
ABNORMAL SENSATION IN EYE1
ABNORMAL FAECES1
ABNORMAL BEHAVIOUR1
ABDOMINAL TENDERNESS1
ABDOMINAL SYMPTOM1
ABDOMINAL PAIN LOWER1
ABDOMINAL ADHESIONS1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
O43570 13 Carbonic anhydrase 12 CAH12_HUMAN
P00403 1100 Cytochrome c oxidase subunit 2 COX2_HUMAN
P00918 43 Carbonic anhydrase 2 CAH2_HUMAN
P22748 1340 Carbonic anhydrase 4 CAH4_HUMAN
P23280 572 Carbonic anhydrase 6 CAH6_HUMAN
P35218 912 Carbonic anhydrase 5A, mitochondrial CAH5A_HUMAN
P35354 5 Prostaglandin G/H synthase 2 PGH2_HUMAN
P43166 3900 Carbonic anhydrase 7 CAH7_HUMAN
Q16790 27 Carbonic anhydrase 9 CAH9_HUMAN
Q8N1Q1 425 Carbonic anhydrase 13 CAH13_HUMAN
Q9ULX7 107 Carbonic anhydrase 14 CAH14_HUMAN
Q9Y2D0 88 Carbonic anhydrase 5B, mitochondrial CAH5B_HUMAN



Toxicity information:

Toxicity type: cardiovascular



External links:

ChEBML: CHEMBL865
DrugBank: DB00580